Publications

The Journal of biological chemistry

Characterization and functional analysis of the murine Frat2 gene.

25-06-2004

Genome research

A whole-genome mouse BAC microarray with 1-Mb resolution for analysis of DNA copy number changes by array comparative genomic hybridization

01-01-2004

Nature reviews. Cancer

Conditional mouse models of sporadic cancer.

01-04-2002

Cancer research

Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice.

15-03-2002

Nature genetics

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

01-12-2001

Proceedings of the National Academy of Sciences of the United States of America

Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells.

31-07-2001

EMBO reports

A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent.

01-04-2001

Experimental cell research

Mouse models for sporadic cancer.

10-03-2001

Cancer gene therapy

Lymphoid abnormalities in CD40 ligand transgenic mice suggest the need for tight regulation in gene therapy approaches to hyper immunoglobulin M (IgM) syndrome

01-10-2000

Genes & development

Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum.

15-04-2000

Mechanisms of development

In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3.

01-11-1999

Oncogene

Overexpression of Frat1 in transgenic mice leads to glomerulosclerosis and nephrotic syndrome, and provides direct evidence for the involvement of Frat1 in lymphoma progression.

28-10-1999

The EMBO journal

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1

02-08-1999

Cancer research

Identification and characterization of collaborating oncogenes in compound mutant mice.

01-04-1999

The EMBO journal

Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas.

03-02-1997

Journal of virology

Characterization of pal-1, a common proviral insertion site in murine leukemia virus-induced lymphomas of c-myc and Pim-1 transgenic mice.

01-01-1997

Biochimica et biophysica acta

Retroviral insertional mutagenesis as a strategy to identify cancer genes.

16-05-1996

Cold Spring Harbor symposia on quantitative biology

Mouse model systems to study multistep tumorigenesis.

01-01-1994

Plant molecular biology

Preparation of megabase-sized tomato DNA and separation of large restriction fragments by field inversion gel electrophoresis (FIGE)

01-03-1989

Oncotarget

Cooperation between BRCA1 and vitamin D is critical for histone acetylation of the p21waf1 promoter and growth inhibition of breast cancer cells and cancer stem-like cells

Breast Cancer Research: BCR