Thesis defense Ellen Derissen - do medicines make it into cells?

27-01-2020

How can physicians optimally treat cancer patients with pyrimidine analogues, an important class of drugs used in oncology?

PhD student Ellen Derissen investigated to what extend those medicines manage to get into the patients' cells and be activated once arrived. Only then they can kill cancer cells. She developed two analytical assays to measure the active form of such drugs in cells. The amount of activated drug in cells appears to differ substantially between patients. More knowledge of these drug concentrations will hopefully improve the treatment of patients with this type of medicine.

Thesis defense Ellen Derissen - do medicines make it into cells?

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