Postdoctoral Researcher - Alternative Lipid Synthesis in Cancer

The Brummelkamp laboratory (Division of Biochemistry) is seeking a motivated postdoctoral fellow to study how alternative triglyceride synthesis – a recently discovered metabolic pathway (McLelland et al., Nature 2023) – contributes to tumor growth and metastasis.

Cancer cells rewire their metabolism to adapt to nutrient limitations, and understanding these metabolic adaptations is key to developing new therapeutic strategies. In this project, we aim to define how lipid biosynthetic pathways support cancer cell survival and dissemination. Using a combination of cellular and in vivo models, the postdoctoral researcher will investigate how tumors dynamically alter lipid metabolism in response to their microenvironment.

The position is embedded in a collaborative research environment, with exposure to cutting-edge genetics, cell biology and proteomics/lipidomics technologies. The candidate will work closely with a technician and senior postdoctoral fellow dedicated to the project.

Scientific Environment
The Netherlands Cancer Institute (NKI), located in Amsterdam, is a leading cancer research institute affiliated with the Antoni van Leeuwenhoek (AvL) hospital. It fosters an interdisciplinary environment where fundamental, translational, and clinical researchers collaborate to advance cancer treatment. The Brummelkamp group in the Division of Biochemistry is an international and stimulating laboratory, where trainees have access to state-of-the-art equipment and facilities.
 

We are looking for a highly motivated postdoctoral researcher with:

• A PhD in Biomedical Sciences, Molecular Biology, Cancer Biology, or a related field;
• Strong expertise in molecular biology and cell culture; 
• Excellent organizational, interpersonal, and communication skills;
• The ability to work both independently and collaboratively in a dynamic research environment.

• The terms of employment will be in accordance with the CAO Hospitals;
• You will join a dynamic international research group;
• You will collaborate with scientists and clinicians with expertise in different disciplines; 
• Your temporary employment will be for a period of 2 years, with a possible extension; 
• Depending on experience, the gross salary ranges from €4.457,- to €5.084,- per month (FWG 55 scale, CAO Hospitals); 
• In addition, you will receive a fixed end-of-year bonus (8,33%) and you will receive 8,33% holiday pay; 
• Your travel expenses will be reimbursed at € 0,23 per km; 
• Free parking at the Antoni van Leeuwenhoek is also part of the package; 
• Personnel is stimulated to use public transport and bicycle and therefore we offer an interesting arrangement for bikers; 
• Amsterdam is a stunning city with many cultural amenities. The institute is located within a 20-minute tram or bicycle ride from the center of Amsterdam and within 20 minutes from Schiphol airport by car, bus or bicycle.

Your application letter, CV and contact information of 2 references can be attached to the application link on our website. 
Ensure that your references information is attached together with your cover letter, as there is no option to submit them separately.
Apply by the 'Apply now'  button at the bottom of the page.
Take note: please respond to this vacancy only via the application button, and not via email.

Deadline: 
This vacancy is open until March 1st 2025.

Want more information?
For inquiries, please contact:
Gian-Luca McLelland g.mclelland@nki.nl
Thijn Brummelkamp t.brummelkamp@nki.nl

The Netherlands Cancer Institute is an equal opportunity employer and values diversity in its workforce.